生命学院陈晓峰攻读博士学位期间取得的研究成果

[1] Chen XF^#, Zhu DL^#, Yang M, Hu WX, Duan YY, Lu BJ, Rong Y, Dong SS, Hao RH, Chen JB, Chen YX, Yao S, Thynn HN, Guo Y, Yang TL. An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation [J], American Journal of Human Genetics, 2018, 102(5):776-793.（SCI: 000432440100005; IF:9.924; 最有学术影响力的国际期刊）

[2] Thynn HN^#, Chen XF^# (共同一作), Hu WX, Duan YY, Zhu DL, Chen H, Wang NN, Chen HH, Rong Y, Lu BJ, Yang M, Jiang F, Dong SS, Guo Y, Yang TL. An allele-specific functional SNP associated with two systemic autoimmune diseases modulates IRF5 expression by long-range chromatin loop formation [J]. Journal of Investigative Dermatology 2019, DOI: 10.1016/j.jid.2019.06.147.（IF:6.29; 最有学术影响力的国际期刊）

[3] Zhu DL^#, Chen XF^# (共同一作), Hu WX, Dong SS, Lu BJ, Rong Y, Chen YX, Chen H, Thynn HN, Wang NN, Guo Y, Yang TL. Multiple functional variants at the 13q14 risk locus for osteoporosis regulate RANKL expression through long-range super-enhancer [J]. Journal of Bone and Mineral Research, 2018, 33(7):1335-1346.（SCI: 000437284400017; IF:5.711; 最有学术影响力的国际期刊）

[4] Chen XF, Guo MR, Duan YY, Jiang F, Wu H, Dong SS, Thynn HN, Liu CC, Zhang L, Guo Y, Yang TL. Dissecting molecular regulatory mechanisms underlying noncoding susceptibility SNPs associated with 19 autoimmune diseases using multi-omics integrative analysis. bioRxiv 871384; doi: https://doi.org/10.1101/871384.

[5] Dong SS, Guo Y, Yao S, Chen YX, He MN, Zhang YJ, Chen XF, Chen JB, Yang TL. Integrating regulatory features data for prediction of functional disease-associated SNPs [J]. Briefings in Bioinformatics. 2019, 20(1):26-32.（SCI: 000456736200003; IF:9.101; 最有学术影响力的国际期刊）

[6] Dong SS, Guo Y, Zhu DL, Chen XF, Wu XM, Shen H, Chen XD, Tan LJ, Tian Q, Deng HW, Yang TL. Epigenomic Elements Analyses for Promoters Identify ESRRG as a New Susceptibility Gene for Obesity-related Traits [J]. International Journal of Obesity, 2016, 40(7):1170-1176.（SCI: 000379498200019; IF:4.514; 最有学术影响力的国际期刊）

[7] Yao S, Guo Y, Dong SS, Hao RH, Chen XF, Chen YX, Chen JB, Tian Q, Deng HW, Yang TL. Regulatory element-based prediction identifies new susceptibility regulatory variants for osteoporosis [J]. Human Genetics. 2017, 136(8):963-974.（SCI:000405284600004; IF:5.207;最有学术影响力的国际期刊）

[8] Niu HM, Yang P, Chen HH, Hao RH, Dong SS, Yao S, Chen XF, Yan H, Zhang YJ, Chen YX, Jiang F, Yang TL, Guo Y. Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia [J]. Translational Psychiatry. 2019, 9(1):56.（SCI: 000459833200010; IF:5.182）

[9] Zhu DL, Guo Y, Zhang Y, Dong SS, Xu W, Hao RH, Chen XF, Yan H, Yang SY, Yang TL. A functional SNP regulated by miR-196a-3p in the 3'UTR of FGF2 is associated with bone mineral density in the Chinese Population [J]. Human Mutation, 2017, 38.（SCI: 000401141900012; IF:4.45; 最有学术影响力的国际期刊）

[10] 杨波，陈晓峰，段媛媛，郭燕．结合吸烟与遗传因素交互作用鉴定骨质疏松症易感基因 [J]. 西安交通大学学报(医学版)，2018, 213(4):143-150.

[11] 杨铁林，陈晓峰，郭燕，朱东丽，卢冰婕，杨熳．一种批量设计融合PCR引物的方法[P]．中国，发明专利．专利号：ZL201610393219.1

[12] 郭燕，杨铁林，董珊珊，陈晓峰．一种基于表观调控元件特征预测复杂疾病易感基因的方法 [P]．中国，发明专利．专利号：ZL201611258007.9

论文题目 建立非编码区疾病易感SNP功能预测方法并结合功能实验解析骨质疏松易感区1p36.12的遗传调控机制

专 业 生物学

学 号 4116013004

公示时间 2020年1月7日

公示地点 生命学院研究生教务办